I nominated HawthoRNe, which is a medical drama on TNT starring a largely PoC cast (largely: more than half of what I think is the primary cast, although if you add recurring minor characters, it's more white). I don't know who all the creators are, but I do know that Jada Pinkett Smith is a producer as well as the star. There are at least five consistent female CoC.

I also nominated Royal Pains, which is not to my knowledge created by a PoC but has character Divya Katdare (and Raj, though he is a more minor character). I'm expecting to request fic involving Divya.