I nominated Donovan's Reef, which is a morality play in the guise of a John Wayne action/romantic comedy. It deals harshly with issues of racial bigotry, corporate connivance and greed, and American beliefs of societal "superiority" and hypocrisy. It was made in the early sixties, so there's still a lot of fail (particularly misogyny), but for its era it was remarkable. Chromatic characters include Leilani, Sally, and Luke Dedham, and most of the background characters. Leilani, Sally, and Luke play Polynesian-American children turned out of their home while their father is gone to live with their "uncle" (John Wayne) so as not to shock their American half-sister visiting from Boston by letting her know of their existence.